Highly active antiretroviral therapy and hospital readmission: comparison of a matched cohort
2006

Impact of HAART on Hospital Readmission in HIV Patients

Sample size: 662 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bohdan Nosyk, Sun Huiying, Li Xin, Palepu Anita, Anis Aslam H

Primary Institution: Canadian HIV Trials Network, St. Paul's Hospital, Vancouver, BC, Canada

Hypothesis

Patients not on HAART would have a higher probability of readmission within one year.

Conclusion

HIV-infected patients who were not on HAART had higher odds of being readmitted to hospital compared to those on HAART.

Supporting Evidence

  • Patients on HAART had lower odds of AIDS hospital readmission.
  • Patients on HAART had significantly lower odds of non-IDU related readmission.
  • Overall readmission rates were lower among patients on HAART.

Takeaway

Patients with HIV who take their medicine (HAART) are less likely to go back to the hospital than those who don't take it.

Methodology

Patients were matched by propensity scores based on sociodemographics and followed for one year to compare readmission rates.

Potential Biases

Potential selection bias due to observational study design.

Limitations

CD4 count at index admission was not controlled for, and treatment history and reasons for not being on HAART were unknown.

Participant Demographics

Patients included were HIV-infected individuals admitted to a specialized HIV/AIDS ward, with varying ages and drug use histories.

Statistical Information

P-Value

< 0.01

Confidence Interval

95% CI, 0.42 – 0.89

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-6-146

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