Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
2008
How Solanaceae Plants Resist Pests
publication
Evidence: moderate
Author Information
Author(s): Kong Lesheng, Ranganathan Shoba
Primary Institution: Temasek Life Sciences Laboratory, National University of Singapore
Hypothesis
The study investigates the evolution and molecular adaptation of Potato type II proteinase inhibitors in Solanaceae plants.
Conclusion
The study provides insights into how Solanaceae plants use gene and domain duplication, structural circular permutation, and molecular adaptation to defend against pests.
Supporting Evidence
- The Pot II family of proteinase inhibitors plays critical roles in plant defense against pests.
- The study classified structural domains in the Pot II family into three types based on linker existence.
- Permuted domains were found to be more stable than original repeat domains.
Takeaway
This study looks at how certain plants protect themselves from pests by changing their proteins over time.
Methodology
The study used computational analysis to investigate the correlation between sequence and structural repeats in the Pot II family of proteinase inhibitors.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website