Evidence of seasonality in the diagnosis of monocytic leukaemia
2002

Seasonality in Monocytic Leukaemia Diagnosis

Sample size: 2311 publication Evidence: moderate

Author Information

Author(s): Eatough J P

Primary Institution: Medical Physics Department, North Staffordshire Royal Infirmary

Hypothesis

Is there a seasonal pattern in the diagnosis of monocytic leukaemia?

Conclusion

There is preliminary evidence suggesting a seasonal variation in the diagnosis of monocytic leukaemia, with peaks in February/March and lows in August/September.

Supporting Evidence

  • Previous studies showed inconsistent results regarding seasonality in leukaemia diagnosis.
  • Analysis of larger data sets revealed significant seasonal variation in monocytic leukaemia diagnoses.
  • February/March had the highest diagnosis rates, while August/September had the lowest.

Takeaway

Doctors found that more people are diagnosed with monocytic leukaemia in the winter than in the summer.

Methodology

Data from the Office of National Statistics was analyzed for every recorded case of monocytic leukaemia in England and Wales from 1974 to 1998.

Limitations

The smallest data set analyzed was too small to reliably determine seasonal variation.

Participant Demographics

Data included all recorded cases of monocytic leukaemia in England and Wales.

Statistical Information

P-Value

P<0.005

Statistical Significance

p<0.005

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600497

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