Assessment of the methodological quality of studies on core outcome sets for respiratory diseases: A systematic review and meta-research study
2025

Assessing the Quality of Studies on Core Outcome Sets for Respiratory Diseases

Sample size: 27 publication Evidence: low

Author Information

Author(s): Liu Mengjuan, Wang Jiajia, Wang Lu, Zhang Xinyi, Hao Ruiyu, Wang Duolao, Chen Tao, Li Jiansheng

Primary Institution: Henan University of Chinese Medicine, Zhengzhou, China

Hypothesis

The methodological quality of studies on core outcome sets for respiratory diseases is unclear and needs assessment.

Conclusion

The methodological quality of studies on core outcome sets for respiratory diseases needs to be further improved.

Supporting Evidence

  • Only three studies fully reported all COS-STAD items.
  • Many studies on COS-RD do not meet international reporting standards.
  • Stakeholder involvement in COS development was often underreported.

Takeaway

This study looked at how well researchers are reporting important outcomes for respiratory disease studies, and found that many are not doing a good job.

Methodology

The study involved searching multiple databases for articles on core outcome sets for respiratory diseases, assessing their methodological quality using established reporting standards.

Potential Biases

Potential bias due to underreporting of stakeholder involvement and lack of patient input in some studies.

Limitations

Some studies began before the publication of international reporting standards, which may affect their compliance.

Participant Demographics

Studies included adults with various respiratory diseases, including COVID-19, COPD, and lung cancer.

Digital Object Identifier (DOI)

10.1371/journal.pone.0316670

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