Fasting Plasma Glucose and C-Reactive Protein in Japanese Adults
Author Information
Author(s): Kawamoto Ryuichi, Tabara Yasuharu, Kohara Katsuhiko, Miki Tetsuro, Kusunoki Tomo, Takayama Shuzo, Abe Masanori, Katoh Tateaki, Ohtsuka Nobuyuki
Primary Institution: Ehime University, Graduate School of Medicine
Hypothesis
Are increased fasting plasma glucose levels associated with elevated high-sensitivity C-reactive protein concentrations by gender?
Conclusion
Fasting plasma glucose levels are associated with increased high-sensitivity C-reactive protein levels, particularly in women.
Supporting Evidence
- hsCRP levels increased significantly with higher fasting plasma glucose in women.
- The study included a large sample size of 1,919 participants.
- The association between FPG and hsCRP was independent of other cardiovascular risk factors.
Takeaway
This study found that higher blood sugar levels can lead to higher inflammation markers, especially in women.
Methodology
Cross-sectional study examining the relationship between fasting plasma glucose and high-sensitivity C-reactive protein in a community-dwelling population.
Potential Biases
Potential confounding factors such as medication for hypertension were not fully controlled.
Limitations
The cross-sectional design limits causal inference, and single blood assessments may introduce misclassification bias.
Participant Demographics
822 men (mean age 61) and 1,097 women (mean age 63) from a Japanese community.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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