Creatinine and Cystatin-C Indices and Sarcopenia in Older Adults
Author Information
Author(s): Jang Jae Young, Shin Hyung Eun, Lee Daehyun, Jung Heeeun, Cho Hyunjin, Lim Nahyun, Won Chang Won, Kim Miji
Primary Institution: Kyung Hee University
Hypothesis
The study examines the long-term relationship between serum creatinine and cystatin-C indices and the incidence of sarcopenia in older adults.
Conclusion
Monitoring pSMI could help predict the onset of sarcopenia in community-dwelling older adults.
Supporting Evidence
- The incidence of sarcopenia was 22.5% in men and 16.7% in women over 6 years.
- Higher pSMI and TBMM were associated with a lower risk of incident sarcopenia.
- pSMI and TBMM showed higher predictive capabilities for sarcopenia compared to other indices.
Takeaway
This study looked at how certain blood tests can help predict if older people will develop muscle loss over time.
Methodology
The study followed 698 older adults over 6 years, measuring various indices related to creatinine and cystatin-C to assess their relationship with sarcopenia.
Participant Demographics
Mean age 75.1 years, 54.4% women.
Statistical Information
Confidence Interval
pSMI: 95% CI=0.223–0.614; TBMM: 95% CI=0.896–0.962
Digital Object Identifier (DOI)
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