7-Hy­droxy-8-isopropyl-1,1,4a-trimethyl-4a,9,10,10a-tetra­hydro-phenanthren-2(1H)-one
2011

Isolation and Structure of a New Compound from Tetraclinis articulata

publication Evidence: moderate

Author Information

Author(s): Benharref Ahmed, Lassaba Essêdiya, Mazoir Noureddine, Daran Jean-Claude, Berraho Moha

Primary Institution: Université Cadi Ayyad, Faculté des Sciences Semlalia

Hypothesis

The study aims to isolate and characterize compounds from the chloroform extract of Tetraclinis articulata wood.

Conclusion

The new compound, totarolenone, was successfully isolated and its structure was confirmed through various analytical techniques.

Supporting Evidence

  • The compound was isolated from a chloroform extract of Tetraclinis articulata wood.
  • The structure was confirmed by NMR spectral analysis and single-crystal X-ray structure.
  • The molecule consists of three fused rings with distinct conformations.

Takeaway

Researchers found a new substance from a plant used in traditional medicine, and they figured out what it looks like.

Methodology

The study involved extracting the wood powder of Tetraclinis articulata with chloroform using a Soxhlet apparatus and analyzing the isolated compound using NMR and X-ray crystallography.

Limitations

The absolute configuration of the compound could not be reliably determined due to the absence of significant anomalous scattering.

Digital Object Identifier (DOI)

10.1107/S1600536811009561

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