Hyoscine-N-butyl bromide for labor progress in first-time mothers
Author Information
Author(s): Makvandi Somayeh, Tadayon Mitra, Abbaspour Mohammadreza
Primary Institution: Ahvaz Jundishapur University of Medical Sciences
Hypothesis
Does hyoscine-N-butyl bromide (HBB) rectal suppository affect labor progress in primigravid women?
Conclusion
Using HBB rectal suppository can shorten both the active phase and second stage of labor without significant side effects.
Supporting Evidence
- The rate of cervical dilatation was significantly higher in the experimental group.
- The active phase and second stage of labor were significantly shorter in the experimental group.
- There were no significant differences in fetal heart rate, maternal pulse rate, or blood pressure between the groups.
Takeaway
This study found that a special medicine can help women in labor have their babies faster and easier.
Methodology
A randomized double-blind placebo-controlled clinical trial with 130 primigravid women, comparing HBB and placebo during labor.
Limitations
The study was not sufficiently powered to assess adverse neonatal outcomes.
Participant Demographics
Primigravid women aged 18-35 with normal pregnancies and a singleton fetus.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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