(1S,2R,4S)-1-[(Benzyl­amino)­meth­yl]-4-(prop-1-en-2-yl)cyclo­hexane-1,2-diol
2011

Synthesis and Crystal Structure of a New Aminodiol Derivative

publication Evidence: moderate

Author Information

Author(s): Outouch Rachid, Boualy Brahim, Ali Mustapha Ait, Firdoussi Larbi El, Rizzoli Corrado

Primary Institution: Equipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Marrakech, Morocco

Hypothesis

The study investigates the synthesis and structural properties of a new aminodiol derivative of perillyl alcohol.

Conclusion

The synthesized compound exhibits a stable molecular conformation due to intramolecular hydrogen bonding.

Supporting Evidence

  • The compound was synthesized using a known procedure for creating aminodiol derivatives.
  • Intramolecular hydrogen bonding stabilizes the molecular conformation.
  • Intermolecular hydrogen bonds link molecules into chains in the crystal structure.

Takeaway

Scientists made a new chemical compound and found that its structure is held together by special bonds, which help it stay stable.

Methodology

The compound was synthesized through epoxidation followed by ring-opening using benzylamine and a catalyst under solvent-free conditions.

Digital Object Identifier (DOI)

10.1107/S1600536810052323

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