SigWin-detector: a Grid-enabled workflow for discovering enriched windows of genomic features related to DNA sequences
2008
SigWin-detector: A Tool for Analyzing Genomic Features
publication
Evidence: moderate
Author Information
Author(s): Inda Márcia A, van Batenburg Marinus F, Roos Marco, Belloum Adam SZ, Vasunin Dmitry, Wibisono Adianto, van Kampen Antoine HC, Breit Timo M
Primary Institution: University of Amsterdam
Hypothesis
Can an e-Science approach improve the detection of enriched genomic features in DNA sequences?
Conclusion
SigWin-detector is an efficient and reusable tool for discovering enriched windows of genomic features in any sequence of values.
Supporting Evidence
- SigWin-detector can detect regions of increased and decreased gene expression efficiently.
- The tool is based on a modular e-Science approach, making it adaptable for various genomic analyses.
- Improvements in the method significantly reduce computation time from days to minutes.
Takeaway
SigWin-detector helps scientists find important parts of DNA quickly and easily, like a treasure map for genes.
Methodology
The tool was developed using the WS-VLAM workflow management system and includes several reusable modules for detecting enriched genomic features.
Digital Object Identifier (DOI)
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