Reversible Splenial Lesion Syndrome in Neuroleptic Malignant Syndrome
Author Information
Author(s): Al-Edrus SA, Norzaini R, Chua R, Puvanarajah SD, Shuguna M, Muda S
Primary Institution: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia
Hypothesis
Can neuroleptic malignant syndrome cause reversible splenial lesions in the corpus callosum?
Conclusion
This case highlights the need to consider neuroleptic malignant syndrome in the differential diagnosis of reversible splenial lesions.
Supporting Evidence
- The patient had a clinical diagnosis of neuroleptic malignant syndrome.
- Initial MRI showed a lesion in the splenium of the corpus callosum.
- Follow-up MRI 8 weeks later showed complete resolution of the lesion.
Takeaway
A woman with a brain lesion got better after treatment for a serious reaction to her psychiatric medication.
Methodology
The case involved clinical diagnosis, MRI imaging, and laboratory investigations.
Potential Biases
Potential bias in diagnosis due to reliance on clinical presentation and imaging.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
65-year-old female with a history of bipolar disorder.
Digital Object Identifier (DOI)
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