Can weight loss prevent cancer?
2008

Can weight loss prevent cancer?

publication Evidence: moderate

Author Information

Author(s): Wolin K Y, Colditz G A

Primary Institution: Washington University School of Medicine

Hypothesis

Can weight loss prevent cancer?

Conclusion

Weight loss could prevent a major portion of common cancers.

Supporting Evidence

  • Weight gain is associated with increased risk of several cancers, including postmenopausal breast cancer.
  • Obesity increases the risk of colorectal cancer and other cancers.
  • Weight loss after menopause is linked to a reduced risk of breast cancer.

Takeaway

If people lose weight and keep it off, they might avoid getting cancer. This is especially true for breast cancer in women after menopause.

Methodology

The study reviews evidence from previous reports and studies published since 2002 regarding the relationship between weight and various cancers.

Limitations

Limited data exist on the effects of weight gain or weight loss on cancer risk, particularly due to the small number of individuals able to achieve sustained weight loss.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604623

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