Graves' Disease in HIV Patients After Starting Antiretroviral Therapy
Author Information
Author(s): Rasul Samad, Delapenha Robert, Farhat Faria, Gajjala Jhansi, Zahra Syeda Mehreen
Primary Institution: Howard University Hospital
Hypothesis
Can Graves' disease occur as a result of immune reconstitution in HIV-infected individuals after starting HAART?
Conclusion
Graves' disease should be suspected in HIV-infected individuals who show signs of hyperthyroidism despite good control of their HIV.
Supporting Evidence
- Graves' disease can occur in HIV patients after starting HAART.
- Symptoms of hyperthyroidism may develop 8–33 months after initiating therapy.
- 1-2% of HIV-infected patients can present with overt thyroid disease.
Takeaway
Some people with HIV can get a disease called Graves' disease after they start treatment, which can make them feel sick even when their HIV is under control.
Methodology
Case report of four HIV-infected patients who developed Graves' disease after starting HAART.
Potential Biases
Potential bias in case selection and reporting due to the small sample size.
Limitations
The study is based on a small number of cases, limiting generalizability.
Participant Demographics
Four HIV-infected patients, predominantly African American males.
Digital Object Identifier (DOI)
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