Vanadium-Enriched Cordyceps sinensis, a Contemporary Treatment Approach to Both Diabetes and Depression in Rats
2011

Vanadium-Enriched Cordyceps sinensis for Diabetes and Depression in Rats

Sample size: 24 publication Evidence: moderate

Author Information

Author(s): Guo Jianyou, Li ChangYu, Wang Jie, Liu Yongmei, Zhang Jiahui

Primary Institution: Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences

Hypothesis

Can vanadium-enriched Cordyceps sinensis (VECS) effectively manage both diabetes and depression in rats?

Conclusion

The study found that VECS significantly reduced blood glucose levels and improved insulin levels while also decreasing immobility and increasing swimming and climbing behaviors in diabetic rats.

Supporting Evidence

  • VECS treatment led to a significant reduction in blood glucose levels.
  • Serum insulin levels increased significantly after VECS treatment.
  • VECS treatment decreased immobility time in the forced swimming test.

Takeaway

This study shows that a special mushroom can help rats with diabetes feel better and manage their blood sugar.

Methodology

The study used streptozotocin-induced diabetic rats, which were treated with VECS, FMCS, and SV, and their behaviors were assessed using a modified forced swimming test.

Participant Demographics

Wistar rats of either sex weighing 150–200 g.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/ecam/neq058

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