How Moldy Odors Affect Fungi Growth and Toxin Production
Author Information
Author(s): Gong Di, Yan Tingting, Wang Xuexue, Prusky Dov, Long Danfeng, Zhang Ying, Bi Yang, Wang Zonghua
Primary Institution: School of Public Health, Lanzhou University, Lanzhou, China
Hypothesis
PePpoA and PePpoC regulate growth, pathogenicity, and mycotoxin production through C8 MVOC-mediated G protein signaling in Penicillium expansum.
Conclusion
The deletion of ppoA or ppoC reduces growth, pathogenicity, and patulin production in Penicillium expansum.
Supporting Evidence
- Deletion of ppoA decreased C8 MVOC production in P. expansum.
- All C8 MVOCs were not detected in the ΔppoC strain.
- Both mutants showed reduced pathogenicity on apple fruit.
- Patulin production was significantly lower in both mutants compared to the wild type.
- Gene expression involved in cAMP-PKA and PLC/PKC signaling pathways was down-regulated in both mutants.
Takeaway
This study shows that certain proteins in mold can change how the mold grows and produces toxins, which can be harmful to fruits.
Methodology
The study involved creating knockout strains of P. expansum to analyze the effects of ppoA and ppoC deletions on growth, pathogenicity, and patulin production.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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