2-(4-Fluorophenyl)-3-methyl-1H-indole C15H12FN
2011
Study of a New Indole Compound
publication
Author Information
Author(s): David B. Cordes, Guoxiong Hua, Alexandra M. Z. Slawin, J. Derek Woollins
Primary Institution: School of Chemistry, University of St Andrews
Conclusion
The compound forms weak interactions with adjacent indole structures instead of classical hydrogen bonding.
Supporting Evidence
- The compound was synthesized using a new route.
- It does not closely relate to any known structures.
- The indole N—H shows a tendency toward interactions with π systems.
Takeaway
Scientists made a new chemical compound that interacts differently than expected with other similar compounds.
Methodology
The compound was synthesized from 4-fluoro-N-(2-oxo-2-phenylethyl)benzamide and Woollins' reagent, followed by purification and crystallization.
Digital Object Identifier (DOI)
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