IQ as a predictor of functional outcome in schizophrenia: A longitudinal, four-year study of first-episode psychosis
2009

IQ as a Predictor of Functional Outcome in Schizophrenia

Sample size: 54 publication 10 minutes Evidence: moderate

Author Information

Author(s): Verity C. Leeson, Thomas R.E. Barnes, Sam B. Hutton, Maria A. Ron, Eileen M. Joyce

Primary Institution: Imperial College London

Hypothesis

Can IQ be a more reliable predictor of outcomes in first-episode schizophrenia compared to specific cognitive measures?

Conclusion

The study found that general cognitive ability, as measured by IQ, is a more sensitive predictor of functional outcomes in first-episode schizophrenia than specific cognitive measures.

Supporting Evidence

  • Premorbid IQ and IQ at each assessment significantly predicted social function at four-year follow-up.
  • IQ was a stronger predictor of social function than specific cognitive measures.
  • The predictive values of cognition on residual symptoms were less strong.

Takeaway

This study shows that how smart someone is can help predict how well they will do in life after having their first episode of schizophrenia.

Methodology

The study assessed 54 patients with first-episode schizophrenia at three time points over four years, measuring cognitive and social function as well as symptoms.

Potential Biases

Potential biases may arise from the reliance on self-reported measures of social function.

Limitations

The study's findings may not generalize to all schizophrenia patients as it focused on first-episode cases.

Participant Demographics

54 patients (43 male, 10 female), aged 16-55, with first-episode schizophrenia or schizoaffective disorder.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.schres.2008.08.014

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