Rural Versus Urban Genitourinary Cancer Incidence and Mortality in Pennsylvania: 1990–2019
2024

Rural vs Urban Genitourinary Cancer Rates in Pennsylvania

Sample size: 462900 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jonathan Pham, Ahmad N. Alzubaidi, Jay D. Raman, Tullika Garg

Primary Institution: Penn State Health Milton S. Hershey Medical Center

Hypothesis

The study aims to describe the incidence and mortality of genitourinary cancers in rural and urban Pennsylvania counties from 1990 to 2019.

Conclusion

Overall genitourinary cancer incidence and mortality decreased across both rural and urban Pennsylvania counties over three decades.

Supporting Evidence

  • GU cancer incidence decreased in both rural and urban counties.
  • Prostate cancer incidence decreased significantly in both rural and urban areas.
  • Kidney cancer incidence increased in both rural and urban counties.
  • GU cancer mortality decreased in both rural and urban counties.
  • Bladder cancer incidence and mortality remained stable in both types of counties.

Takeaway

This study looked at how many people got and died from certain types of cancers in cities and countryside areas in Pennsylvania over 30 years. It found that fewer people got these cancers and died from them in both places.

Methodology

The study used data from the Pennsylvania Cancer Registry to calculate age-adjusted incidence and mortality rates of prostate, bladder, and kidney cancers from 1990 to 2019.

Potential Biases

Potential bias due to the exclusion of certain cancer types and reliance on a publicly available dataset.

Limitations

The study used a fixed rural-urban classification which may not reflect changes over time and lacked detailed patient and tumor characteristics.

Participant Demographics

The study included data from all new cancer cases diagnosed in Pennsylvania, with a focus on prostate, bladder, and kidney cancers.

Statistical Information

P-Value

p = 0.04 for overall GU cancer incidence in rural counties; p = 0.02 for urban counties.

Confidence Interval

95% CI 0.65–0.83 for treatment likelihood in rural men.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/curroncol31120597

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