Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection
2024

Changes in Visual Cortex After Pediatric Surgery

Sample size: 17 publication

Author Information

Author(s): Liu Tina T., Granovetter Michael C., Maallo Anne Margarette S., Robert Sophia, Fu Jason Z., Patterson Christina, Plaut David C., Behrmann Marlene

Primary Institution: Cold Spring Harbor Laboratory

Hypothesis

How does pediatric cortical resection affect category-selectivity in the visual cortex?

Conclusion

The study shows that pediatric cortical resection can lead to both adherence to and deviations from typical visual cortex organization.

Supporting Evidence

  • The study examined the organization of category-selective responses in the visual cortex.
  • It involved individuals who had undergone VOTC resection during childhood.
  • The research highlighted the potential for cortical plasticity in the visual system.

Takeaway

When kids have brain surgery to remove part of their visual cortex, their brains can change how they recognize things like faces and words.

Methodology

Cross-sectional and longitudinal functional imaging studies comparing individuals with VOTC resection, a control patient, and typically developing matched controls.

Participant Demographics

Individuals with unilateral resection of VOTC during childhood for drug-resistant epilepsy.

Digital Object Identifier (DOI)

10.1101/2024.12.08.627367

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