Chronic immune activation and inflammation as the cause of malignancy
2001
Chronic Inflammation and Cancer
publication
Author Information
Author(s): O'Byrne K J, Dalgleish A G
Primary Institution: University of Leicester
Hypothesis
Chronic inflammatory conditions contribute to the development of malignancy.
Conclusion
Chronic inflammation creates an environment that promotes cancer development, suggesting that targeting inflammation could help reduce cancer incidence.
Supporting Evidence
- Chronic infections are linked to cancer and have oncogenic properties.
- Chronic inflammation can lead to DNA damage and mutations, which may cause cancer.
- Therapeutic interventions that reduce inflammation could lower cancer rates.
Takeaway
When the body is inflamed for a long time, it can lead to cancer. Treating this inflammation might help prevent cancer.
Digital Object Identifier (DOI)
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