Combined Treatment for Advanced Pancreatic Cancer
Author Information
Author(s): Kornek G V, Schratter-Sehn A, Marczell A, Depisch D, Karner J, Krauss G, Haider K, Kwasny W, Locker G, Scheithauer W
Primary Institution: Vienna University Medical School
Hypothesis
The study aims to evaluate the effectiveness and safety of a combined treatment modality including systemic chemotherapy and external beam radiotherapy in patients with locally advanced pancreatic cancer.
Conclusion
The combined radiochemotherapy regimen was tolerable and effective in patients with locally advanced pancreatic cancer.
Supporting Evidence
- Eighteen of the 38 patients had objective remissions to combined radiochemotherapy.
- The median overall survival was 14.0 months.
- 53% of all patients were alive at 12 months.
Takeaway
Doctors tested a new treatment for patients with a serious type of pancreatic cancer, and it helped some people feel better and live longer.
Methodology
Patients received systemic chemotherapy with 5-fluorouracil, leucovorin, and cisplatin, along with external beam radiotherapy, with treatment courses repeated every 4 weeks.
Limitations
The study had a small sample size and was limited to patients with locally advanced pancreatic cancer.
Participant Demographics
All participants had locally advanced pancreatic cancer.
Digital Object Identifier (DOI)
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