Current Drug Delivery Approaches for Tuberculosis Chemotherapy
Author Information
Author(s): du Toit Lisa Claire, Pillay Viness, Danckwerts Michael Paul
Primary Institution: University of the Witwatersrand, Faculty of Health Sciences, Department of Pharmacy and Pharmacology
Hypothesis
The article reviews the current situation in terms of drug delivery approaches for tuberculosis chemotherapy.
Conclusion
Novel drug delivery systems for tuberculosis chemotherapy could improve patient compliance and drug bioavailability.
Supporting Evidence
- Two billion people are infected with Mycobacterium tuberculosis globally.
- Mortality rates of TB can drop to lower than 5% with effective treatment.
- Current anti-TB treatments require long-term multi-drug regimens.
Takeaway
This study looks at new ways to deliver tuberculosis medicine that could help patients take their medicine more easily and effectively.
Methodology
The article reviews various drug delivery systems for tuberculosis treatment, including implant and microparticulate systems.
Limitations
The need for an oral system that addresses rifampicin bioavailability issues remains unfulfilled.
Digital Object Identifier (DOI)
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