Multidrug-Resistant E. coli Linked to Diarrhea in Kenyan Children
Author Information
Author(s): W.K. Sang, J.O. Oundo, J.K. Mwituria, P.G. Waiyaki, M. Yoh, T. Iida, T. Honda
Primary Institution: Kenya Medical Research Institute
Hypothesis
To study the association of multidrug-resistant enteroaggregative Escherichia coli with persistent diarrhea in Kenyan children.
Conclusion
The study found that multidrug-resistant E. coli O44 was the sole bacterial pathogen in four children with persistent diarrhea.
Supporting Evidence
- Bacterial pathogens were found in 27.7% of the samples.
- E. coli O44 was isolated from four patients experiencing persistent diarrhea.
- Disk diffusion testing showed E. coli O44 resistance to multiple antibiotics.
- Further studies are needed to clarify the epidemiology and pathogenesis of EAggEC infection.
Takeaway
Doctors found a type of E. coli that doesn't respond to many medicines in kids with long-lasting diarrhea in Kenya.
Methodology
Stool specimens were collected from outpatients under 5 years of age and tested for pathogenic organisms using standard methods.
Limitations
Tests for parasitic causes of persistent diarrhea were not performed.
Participant Demographics
Children under 5 years of age from different communities in Kenya.
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