Ethyl 5-{[(E)-2-(isonicotinoyl)hydrazinyl­idene]methyl}-3,4-dimethyl-1H-pyrrole-2-carboxyl­ate dihydrate
2011

Crystal Structure of a Hydrazone Compound

publication Evidence: moderate

Author Information

Author(s): Zhang Zhao-Po, Wang Yuan, Lu Ming-Jia, Jia Lei-Wei, Qiao Hong-Chang

Primary Institution: Henan Polytechnic University

Conclusion

The study presents the crystal structure of a hydrazone compound with specific dihedral angles and hydrogen bonding interactions.

Supporting Evidence

  • The dihedral angle between the pyrrole and pyridine rings is 7.12°.
  • Intermolecular hydrogen bonds link the hydrazone and water molecules into double layers.
  • The crystal packing shows weak π–π interactions between neighboring hydrazone molecules.

Takeaway

Scientists looked at a special chemical structure and found how its parts fit together and interact with each other.

Methodology

The compound was synthesized by mixing isonicotinohydrazide and ethyl 5-formyl-3,4-dimethyl-1H-pyrrole-2-carboxylate in ethanol, followed by crystallization.

Digital Object Identifier (DOI)

10.1107/S1600536811017132

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