LONGITUDINAL AUTOREGRESSIVE AND CROSS-LAGGED EFFECTS BETWEEN FRAILTY AND COGNITIVE FUNCTION OVER 14 YEARS
2024
Effects of Frailty on Cognitive Function Over 14 Years
Sample size: 3853
publication
Evidence: moderate
Author Information
Author(s): Kim Min Jung, Park Chang Gi
Primary Institution: Gachon University, Incheon, Republic of Korea; University of Illinois Chicago, Chicago, Illinois, United States
Hypothesis
Does frailty lead to cognitive impairment or vice versa?
Conclusion
Frailty and cognitive function have significant reciprocal relationships that increase over time, suggesting they may influence each other.
Supporting Evidence
- The study found significant reciprocal causal relationships between frailty and cognitive impairment.
- Frailty showed consistently higher autoregressive coefficients than cognitive impairment over the 14-year period.
- Early interventions targeting either frailty or cognitive impairment may have beneficial effects on both conditions.
Takeaway
As people get frail, their thinking can get worse, and the other way around too. Helping one might help the other.
Methodology
The study used a random-intercept cross-lagged panel model to analyze data from the Korean Longitudinal Study of Aging.
Participant Demographics
Adults aged 45 years or older from a nationally representative sample in Korea.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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