Fixation of Expression Divergences by Natural Selection in Arabidopsis Coding Genes
2024

Natural Selection and Gene Expression in Arabidopsis

Sample size: 20729 publication 10 minutes Evidence: high

Author Information

Author(s): Qi Cheng, Wei Qiang, Ye Yuting, Liu Jing, Li Guishuang, Liang Jane W., Huang Haiyan, Wu Guang

Primary Institution: College of Life Science, Shaanxi Normal University

Hypothesis

Whether and how expression divergences and coding sequence divergences coevolve is not clear.

Conclusion

The study suggests that expression divergences of coding genes are selectively fixed by natural selection, providing a framework for trait diversification and speciation.

Supporting Evidence

  • Gene expression divergences are anti-correlated with gene ages.
  • New genes have lower expression levels.
  • Genes specifically expressed in a sample have a higher phylostratum than broadly expressed genes.
  • Positive selection is a major driver for the origin and evolution of Arabidopsis genes.
  • Lower expression abundance is associated with faster gene evolution.

Takeaway

This study found that genes that change how much they are expressed can help plants adapt and evolve, showing that natural selection plays a big role in this process.

Methodology

The study used transcriptomes and evolutionary proxies to analyze gene expression divergences among differentiated cells and tissues in Arabidopsis.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3390/ijms252413710

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