Predicting Fluid Responsiveness in Cardiac Surgery Patients
Author Information
Author(s): Barbon E, Caliandro F, Kamdar J, Puntis M, Meeran H, Rhodes A, Dewhurst A, Cecconi M
Primary Institution: St Georges Hospital, London, UK
Hypothesis
Can dynamic indices like pulse pressure variation and stroke volume variation predict fluid responsiveness in cardiac surgery patients?
Conclusion
Dynamic indices measured by LiDCO™rapid are effective in predicting fluid responsiveness in patients after cardiac surgery.
Supporting Evidence
- Seven out of 16 patients responded positively to the fluid challenge.
- PPV and SVV were significantly different between responders and nonresponders.
- The best cut-off for PPV was >13.5% with 79% sensitivity.
- The best cut-off for SVV was >10.5% with 84% sensitivity.
Takeaway
Doctors can use special measurements to tell if heart surgery patients need more fluids after their operation.
Methodology
This was a prospective observational study involving fluid challenges in cardiac surgery patients.
Participant Demographics
16 patients, 5 females and 11 males, average age 70 years.
Statistical Information
P-Value
P = 0.003 for PPV, P = 0.0006 for SVV
Confidence Interval
(0.61 to 0.92) for PPV, (0.67 to 0.93) for SVV
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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