Cell surface antigens in renal tumour cells: detection by immunoluminescence and enzymatic analysis
2001
Detection of Cell Surface Proteins in Renal Tumor Cells
Sample size: 2
publication
Author Information
Author(s): Laube F, Göhring B, Sann H, Willhardt I
Primary Institution: Institute of Physiological Chemistry, Hollystr. 1
Conclusion
Different renal cell carcinoma cell lines express varying levels of specific cell surface proteins and enzyme activities.
Supporting Evidence
- Two renal cell carcinoma cell lines were characterized for their cell surface proteins.
- The immunoluminescent technique was used to detect protein localization.
- Different levels of uPA and APN were found in the two cell lines.
- ICAM-1 and CD44(v6) levels varied significantly between the cell lines.
Takeaway
Scientists studied two types of kidney cancer cells to see what proteins they have on their surface, which helps understand how these cells behave.
Methodology
The study used immunoluminescence and enzymatic analysis to detect and characterize cell surface proteins in renal cell carcinoma cell lines.
Digital Object Identifier (DOI)
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