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Conclusion

This book is a valuable resource for researchers interested in the effects of metal ions on nucleic acid structures and properties.

Chapter 1 discusses methodological problems in molecular modeling of metal complexes with nucleic acids.
Chapter 2 presents new receptor molecules that bind selectively to thymine.
Chapter 3 reviews the properties of metallocene complexes relevant to their cytostatic activity.
Chapter 4 summarizes the active role of the DNA double helix in adduct transformation.
Chapter 5 surveys the chemistry of trans-(NH3)2PtCl2 and its reactions with nucleic acids.
Chapter 6 draws conclusions on interactions between metal ions and multiple-stranded DNA.
Chapter 7 discusses the interaction of ruthenium complexes with DNA.
Chapter 20 demonstrates the therapeutic relevance of the Fe(II)-BLM complex in RNA cleavage.

This book talks about how metal ions interact with DNA and RNA, which is important for understanding their roles in biology.