Identifying psychosocial predictors and developing a risk score for preterm birth among Kenyan pregnant women
2024

Risk Factors for Preterm Birth in Kenyan Pregnant Women

Sample size: 4084 publication 10 minutes Evidence: moderate

Author Information

Author(s): Anna Larsen, Jillian Pintye, Felix Abuna, Julia C. Dettinger, Laurén Gomez, Mary M. Marwa, Nancy Ngumbau, Ben Odhiambo, Barbra A. Richardson, Salphine Watoyi, Joshua Stern, John Kinuthia, Grace John-Stewart

Primary Institution: University of Washington

Hypothesis

What demographic, clinical, and psychosocial factors predict preterm birth among Kenyan women?

Conclusion

Preterm birth was associated with several social factors that could be addressed through interventions.

Supporting Evidence

  • 19% of women experienced preterm birth.
  • Being unmarried increased the risk of preterm birth by 29%.
  • Lower educational attainment was associated with a higher risk of preterm birth.
  • Women with mild-to-severe depressive symptoms had a 46% higher risk of preterm birth.

Takeaway

One in five pregnant women in Kenya had preterm births, and factors like being unmarried or having low social support increased the risk.

Methodology

Data was collected from a prospective study involving HIV-negative women attending antenatal clinics, assessing various psychosocial factors and using Cox proportional hazards models for analysis.

Potential Biases

Potential selection bias due to differential enrollment by exposure and outcome status.

Limitations

The risk score did not account for unmeasured factors that may influence preterm birth.

Participant Demographics

Median maternal age was 24 years, with 57.1% being adolescents or young women under 25, and 84.8% were married or living with a partner.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 1.2–1.7

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/s12884-024-07058-x

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