Incidence of and Risk Factors for Dementia in the Ibadan Study of Aging
2011

Incidence of Dementia in Yoruba Nigerians

Sample size: 1225 publication 10 minutes Evidence: moderate

Author Information

Author(s): Oye Gureje, Adesola Ogunniyi, Lola Kola, Taiwo Abiona

Primary Institution: University of Ibadan, University College Hospital

Hypothesis

What is the incidence of dementia and its risk factors in elderly Yoruba Nigerians?

Conclusion

The incidence of dementia in Yoruba Nigerians is higher than previously reported, with social isolation being a significant risk factor.

Supporting Evidence

  • 85 participants developed dementia at the 3-year follow-up.
  • The estimated incidence of dementia was 21.85 per 1,000 person-years.
  • Women had a higher incidence of dementia than men.
  • Incidence increased with age, with older participants at greater risk.
  • Poor social engagement at baseline was linked to higher dementia risk.

Takeaway

This study found that many older people in Nigeria are getting dementia, especially if they are isolated from family and friends.

Methodology

In-home assessments were conducted on a community cohort selected using multistage clustered sampling, with follow-up assessments approximately 39 months later.

Potential Biases

Older participants who died by follow-up were significantly older than those who were successfully followed up.

Limitations

High attrition rate due to deaths and loss to follow-up may underestimate the true incidence of dementia.

Participant Demographics

Participants were elderly Yoruba Nigerians aged 65 and older, with a mix of urban, semiurban, and rural residents.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI = 17.67–27.03

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1111/j.1532-5415.2011.03374.x

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