Examining warfarin underutilization rates in patients with atrial fibrillation: Detailed chart review essential to capture contraindications to warfarin therapy
2008

Warfarin Use in Atrial Fibrillation Patients

Sample size: 364 publication Evidence: moderate

Author Information

Author(s): Ajay Srivastava, Michael Hudson, Ihab Hamoud, Joao Cavalcante, Chetan Pai, Scott Kaatz

Primary Institution: Henry Ford Hospital

Hypothesis

Are the rates of warfarin underutilization in patients with atrial fibrillation accurately assessed through chart reviews?

Conclusion

Only 7.1% of ideal candidates for warfarin therapy were not receiving it after detailed medical chart review.

Supporting Evidence

  • 54.6% of patients received warfarin anticoagulation.
  • 29.5% of patients had documented reasons for not prescribing warfarin.
  • Only 7.1% of patients had no documented reasons for the lack of warfarin use.

Takeaway

Many patients who should be on warfarin aren't getting it, but when doctors check their charts, most have good reasons for not prescribing it.

Methodology

Medical records of 364 patients with atrial fibrillation were reviewed to assess warfarin use and contraindications.

Potential Biases

Potential bias due to reliance on physician documentation for contraindications.

Limitations

The study was limited to a single center and relied on available medical record content.

Participant Demographics

Patients included were atrial fibrillation patients, with a notable percentage being elderly and African American.

Statistical Information

P-Value

0.004

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-9560-6-6

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