Tissue remodeling: a mating-induced differentiation program for the Drosophila oviduct
2008

Mating Triggers Changes in the Drosophila Oviduct

Sample size: 24 publication 10 minutes Evidence: high

Author Information

Author(s): Kapelnikov Anat, Rivlin Patricia K, Hoy Ronald R, Heifetz Yael

Primary Institution: Department of Entomology, The Hebrew University, Rehovot, Israel

Hypothesis

Mating mediates the last stages of oviduct differentiation in which organ-specific specializations arise.

Conclusion

Mating triggers the late differentiation of the oviduct, leading to structural changes that enhance its function.

Supporting Evidence

  • Mating induces changes in the oviduct that facilitate egg passage.
  • Ultrastructural changes in the oviduct are consistent with muscle and epithelial differentiation.
  • Increased innervation of the oviduct is observed post-mating.
  • Muscle differentiation is enhanced in the oviduct after mating.
  • Changes in cytoskeletal protein abundance are linked to mating.
  • Early mating increases female fecundity.

Takeaway

When female fruit flies mate, their egg transport tubes change to help them lay more eggs.

Methodology

Electron and confocal microscopy were used to analyze the ultrastructure of the oviduct in unmated and mated females.

Limitations

The study primarily focuses on the immediate post-mating changes and does not explore long-term effects.

Participant Demographics

3-day-old female Drosophila melanogaster

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-213X-8-114

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