Intraspecific ITS Variability in the Kingdom Fungi as Expressed in the International Sequence Databases and Its Implications for Molecular Species Identification
2008

Intraspecific ITS Variability in Fungi

Sample size: 4185 publication Evidence: moderate

Author Information

Author(s): Nilsson R. Henrik, Kristiansson Erik, Ryberg Martin, Hallenberg Nils, Larsson Karl-Henrik

Primary Institution: Department of Plant and Environmental Sciences, University of Gothenburg

Hypothesis

Can intraspecific ITS variability in the fungi be captured in one generally applicable yet stringent interval, such as 0–3%?

Conclusion

The study found substantial intraspecific ITS variability in fungi, indicating that a single threshold for species delimitation is not applicable across the kingdom.

Supporting Evidence

  • The study found that the variability of the ITS region does not correlate easily with taxonomic affiliation.
  • Results indicate that the canonical 3% threshold for intraspecific variation is not universally applicable across all fungi.
  • Some species showed low or no intraspecific variability, while others exhibited significant variability.

Takeaway

Fungi can be very different from each other even within the same species, making it hard to use a simple rule to tell them apart.

Methodology

The study analyzed 4185 fungal species using data from international sequence databases, focusing on the variability of the internal transcribed spacer (ITS) region.

Potential Biases

Potential biases arise from the reliance on public databases, which may contain misidentified or poorly classified sequences.

Limitations

The study is constrained by the taxonomic reliability of public sequence databases and the presence of misidentified sequences.

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