Development of the Immune System
1997
Development of the Immune System
publication
Author Information
Author(s): Anne Durandy
Primary Institution: Institut National de la Santé et de la Recherche Médicale U429, Hôpital Necker-Enfants Malades, Paris, France
Conclusion
The study outlines the development of the immune system in fetuses and neonates, highlighting their susceptibility to infections due to incomplete immune development.
Supporting Evidence
- Immune defense mechanisms begin early during fetal life but are not fully developed at birth.
- T and B lymphocyte differentiation occurs at specific gestational weeks.
- Neonates have a selective impairment in lymphokine production.
- Natural Killer cells are present and functional by 6 weeks of gestation.
- Specific antibody synthesis begins as early as 20-24 weeks of gestation.
Takeaway
Babies are born with an immune system that isn't fully developed, making them more likely to get sick. They start building their immunity while still in the womb.
Want to read the original?
Access the complete publication on the publisher's website