Conjugation of visual enhancers in lateral flow immunoassay for rapid forensic analysis: A critical review
2025

Using Visual Enhancers in Lateral Flow Tests for Forensic Analysis

publication 10 minutes Evidence: moderate

Author Information

Author(s): Dede Maria, van Dam Annemieke

Primary Institution: Amsterdam UMC, University of Amsterdam

Hypothesis

The review aims to identify the most suitable visual enhancers for lateral flow immunoassays in forensic applications.

Conclusion

The study suggests that carbon nanoparticles are the most effective visual enhancers for lateral flow assays in forensic trace analysis.

Supporting Evidence

  • Lateral flow immunoassays are gaining popularity in forensic science due to their rapid results.
  • Carbon nanoparticles provide high sensitivity and stability for detecting trace evidence.
  • The review highlights the importance of selecting appropriate visual enhancers for effective forensic analysis.

Takeaway

This study looks at different ways to make tests for crime scene evidence faster and better by using special materials that help show results more clearly.

Methodology

The review compares various visual enhancers used in lateral flow immunoassays based on criteria like sensitivity, reproducibility, and cost.

Limitations

The review does not provide experimental data or specific case studies to validate the proposed enhancers.

Digital Object Identifier (DOI)

10.1007/s00216-024-05565-6

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