Avian Influenza Virus (H5N1) Replication in Feathers of Domestic Waterfowl
2008

Avian Influenza Virus (H5N1) in Feathers of Domestic Waterfowl

Sample size: 8 publication Evidence: moderate

Author Information

Author(s): Yamamoto Yu, Nakamura Kikuyasu, Okamatsu Masatoshi, Yamada Manabu, Mase Masaji

Primary Institution: National Institute of Animal Health, Tsukuba, Ibaraki, Japan

Hypothesis

Can avian influenza virus (H5N1) replicate in the feathers of domestic waterfowl?

Conclusion

The study found that H5N1 can replicate in the feather epidermal cells of domestic ducks and geese, even in birds that show no clinical signs of infection.

Supporting Evidence

  • Viral antigens were detected in the feather epidermal cells of infected birds.
  • Virus isolation from the skin was positive in some inoculated birds.
  • Ultrastructural observations showed virions in feather epidermal cells.
  • All birds inoculated with one of the virus strains tested positive for virus isolation.

Takeaway

This study shows that sick birds can have the flu virus in their feathers, which might help spread the virus to other birds.

Methodology

The study involved inoculating domestic ducks and geese with two different H5N1 virus genotypes and examining their feathers and skin for viral replication.

Limitations

The study may not account for individual differences in susceptibility among birds.

Participant Demographics

The study involved domestic ducks and geese, specifically Aigamo ducks and domestic geese.

Digital Object Identifier (DOI)

10.3201/eid1401.071036

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