Pea Protein Reduces Food Intake in Lean and Obese Men
Author Information
Author(s): Geraedts Maartje C. P., Troost Freddy J., Munsters Marjet J. M., Stegen Jos H. C. H., de Ridder Rogier J., Conchillo Jose M., Kruimel Joanna W., Masclee Ad A. M., Saris Wim H. M.
Primary Institution: Maastricht University Medical Center
Hypothesis
Does intraduodenal administration of intact dietary proteins induce stronger effects on satiety hormone release and satiation compared to orally ingested dietary proteins?
Conclusion
Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese subjects, with a greater effect observed in obese individuals.
Supporting Evidence
- Intraduodenal protein administration led to a significant reduction in food intake compared to placebo.
- Obese subjects showed a greater increase in CCK levels after intraduodenal protein administration than lean subjects.
- Both lean and obese subjects reported decreased feelings of hunger after intraduodenal protein treatment.
Takeaway
Giving protein directly into the small intestine helps people feel less hungry and eat less food, especially for those who are overweight.
Methodology
Twenty male subjects received either pea protein or placebo through oral or intraduodenal routes, and their appetite and hormone levels were measured.
Potential Biases
Potential bias due to the single-blind design and the small sample size.
Limitations
The study only included male subjects, which may limit the generalizability of the findings.
Participant Demographics
Twenty male subjects, 10 lean (BMI: 23.0) and 10 obese (BMI: 33.4).
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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