Slipins: ancient origin, duplication and diversification of the stomatin protein family
2008
The Evolution of Stomatin-like Proteins
publication
Evidence: moderate
Author Information
Author(s): Green Jasper B, Young J Peter W
Primary Institution: Department of Biology, University of York, UK
Hypothesis
The study investigates the ancient origin, duplication, and diversification of the stomatin protein family.
Conclusion
Stomatin-like proteins originated from an ancient duplication event early in prokaryotic evolution.
Supporting Evidence
- Stomatin-like proteins are found in all three domains of life.
- The study proposes a new nomenclature for stomatin-like proteins based on their phylogeny.
- Phylogenetic analysis revealed at least four distinct groups of stomatin family members.
Takeaway
Stomatin-like proteins are very old and have changed a lot over time, but we still don't know exactly what they do.
Methodology
Phylogenetic analysis of stomatin-like proteins was conducted using amino acid sequences retrieved from various databases.
Limitations
The study does not clarify the specific functions of stomatin-like proteins despite their evolutionary significance.
Digital Object Identifier (DOI)
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