Common Variable Immunodeficiency Associated with Hepatosplenic T-Cell Lymphoma Mimicking Juvenile Systemic Lupus Erythematosus
2011
Common Variable Immunodeficiency and T-Cell Lymphoma in a Young Girl
Sample size: 1
publication
Evidence: low
Author Information
Author(s): A. A. Jesus, C. A. Silva, Dorna M., A. C. Pastorino, M. Carneiro-Sampaio
Primary Institution: Children's Hospital, São Paulo, Brazil
Hypothesis
CVID can be associated with T-cell lymphoma that mimics juvenile systemic lupus erythematosus.
Conclusion
The association of CVID and hepatosplenic T-cell lymphoma may simulate JSLE diagnosis.
Supporting Evidence
- CVID is a disorder that can lead to infections and autoimmune diseases.
- The patient had symptoms of both CVID and juvenile systemic lupus erythematosus.
- The patient died two months after treatment due to septic shock from pneumonia.
Takeaway
A young girl with a rare immune disorder developed a type of cancer that looked like another disease, but it was actually a lymphoma.
Methodology
Case report detailing the clinical history, laboratory findings, and treatment of a patient.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
An 8-year-old female patient.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website