Adenovirus Type 7 Outbreak in Croatia
Author Information
Author(s): Trogrlic Antea, Mrcela Dina, Budimir Mrsic Danijela, Jukic Ivana, Sardelic Sanda, Tabain Irena, Hruskar Željka, Nonkovic Diana, Markic Josko, Pavicic Ivelja Mirela
Primary Institution: University Hospital of Split
Hypothesis
What are the clinical and radiological features of an adenovirus type 7 outbreak?
Conclusion
The outbreak of adenovirus type 7 in Split-Dalmatia County resulted in severe pneumonia primarily in immunocompetent adults.
Supporting Evidence
- An unusual increase in adenovirus pneumonia was observed, especially in adults.
- Most patients with severe pneumonia were immunocompetent adults without significant medical history.
- Adenovirus type 7 was predominantly isolated from patients with pneumonia.
- Complications such as pulmonary embolism were noted in previously healthy young adults.
Takeaway
A lot of people got sick from a virus called adenovirus, especially adults, and some got really sick with pneumonia.
Methodology
This was a retrospective study analyzing clinical, laboratory, radiological, and microbiological features of adenovirus infections in patients admitted to a hospital.
Potential Biases
Potential bias due to the observational nature of the study and limited serotyping.
Limitations
The study was retrospective and had limited control over the sampling and predictor variables.
Participant Demographics
The study included 185 patients, with 52 adults and 133 children, ages ranging from 1 month to 59 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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