Psychological features of systemic sclerosis: results from an observational study
2024

Psychological Features of Systemic Sclerosis

Sample size: 300 publication 10 minutes Evidence: moderate

Author Information

Author(s): Romanazzo Sara, Rometsch Caroline, Marangoni Alessia, Guiducci Serena, Cosci Fiammetta

Primary Institution: University of Florence, Florence, Italy

Hypothesis

What are the mental disorders and psychological features in patients with systemic sclerosis compared to healthy subjects?

Conclusion

Patients with systemic sclerosis exhibit significant psychological distress and mental disorders, which require assessment and intervention.

Supporting Evidence

  • Major depressive episode and panic disorder were more prevalent among patients with systemic sclerosis.
  • SCL-90-R somatization and depression were more severe in systemic sclerosis patients.
  • Psychological wellbeing was poorer in patients with systemic sclerosis compared to healthy controls.
  • The final model accounted for 20.4% of variance in psychological features related to systemic sclerosis.

Takeaway

People with a disease called systemic sclerosis often feel sad and anxious, and they need help to feel better.

Methodology

The study compared 200 patients with systemic sclerosis to 100 healthy subjects using various psychological assessments.

Potential Biases

Selection bias may affect the generalizability of results as participants might have had higher motivation and better health.

Limitations

The study had a monocentric design and potential selection bias due to voluntary participation.

Participant Demographics

Participants were mainly females (91%) with a mean age of approximately 59 years.

Statistical Information

P-Value

p<0.001

Confidence Interval

95%CI: 9.540–85.255

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fmed.2024.1473587

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