Multidrug and Toxic Compound Extrusion Transporters: Ubiquitous Multifaceted Proteins in Microbes, Plants, and Their Interactions
2024

Multidrug and Toxic Compound Extrusion Transporters in Microbes and Plants

publication Evidence: moderate

Author Information

Author(s): Chiara Pastacaldi, Dario Gaudioso, Stefania Tegli

Primary Institution: Università degli Studi di Firenze

Hypothesis

What roles do multidrug and toxic compound extrusion (MATE) transporters play in the interactions between microbes and plants?

Conclusion

MATE transporters are crucial for the efflux of toxic compounds and play diverse roles in both microorganisms and plants, particularly in drug resistance and plant defense mechanisms.

Supporting Evidence

  • MATE transporters are involved in the efflux of toxic compounds in both plants and microorganisms.
  • Studies show that MATE transporters play a role in drug resistance in bacteria.
  • Plant MATE transporters are crucial for the transport of secondary metabolites and stress responses.
  • Research indicates that MATE transporters are involved in plant-pathogen interactions.

Takeaway

MATE transporters help plants and microbes get rid of harmful substances, which is important for their survival and health.

Methodology

This review summarizes findings from over 600 scientific publications on MATE transporters.

Limitations

The functional and structural characterizations of MATE transporters in microorganisms are still limited.

Digital Object Identifier (DOI)

10.3390/microorganisms12122433

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