Antioxidant and longevity inducing properties of coconut water on human dermal fibroblasts
2024

Coconut Water's Antioxidant and Longevity Effects

Sample size: 20 publication 10 minutes Evidence: moderate

Author Information

Author(s): Sarun Na Nakorn, Dokduang Hasaya, Namwat Nisana, Klanrit Poramate, Wangwiwatsin Arporn, Promraksa Bundit, Sitthirak Sirinya, Seaban Tinnapat, Watcharin Loilome

Primary Institution: Khon Kaen University

Hypothesis

This study aims to investigate and compare the bioactive metabolites in coconut water from various Thai coconut varieties and their effects on antioxidant activity and longevity.

Conclusion

Coconut water has antioxidant properties and can promote longevity in human dermal fibroblasts by reducing oxidative stress.

Supporting Evidence

  • Coconut water contains 27 identified metabolites including sugars, organic acids, and phenolic compounds.
  • Coconut water significantly reduces cytosolic oxidation in human dermal fibroblasts.
  • Breeding coconut varieties have higher antioxidant-bioactive metabolites compared to traditional varieties.
  • Coconut water modulates the expression of proteins involved in the longevity pathway.

Takeaway

Coconut water is good for you because it helps your skin cells stay healthy and live longer by fighting off bad stuff that can hurt them.

Methodology

The study used metabolomic analysis and multivariate data approaches to evaluate the antioxidant activity and potential health benefits of coconut water.

Limitations

The study was conducted in vitro, and further research is needed to confirm the findings in vivo.

Participant Demographics

Human dermal fibroblasts (HDFs) cell line was used for the experiments.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.heliyon.2024.e41010

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