Microembolic Signals in Acute Ischemic Stroke
Author Information
Author(s): Eleni Bakola, Lina Palaiodimou, Odysseas Kargiotis, Apostolos Safouris, Klearchos Psychogios, Theodoros Karapanayiotides, Christos Moschovos, Vijay K. Sharma, Mark N. Rubin, João Sargento Freitas, Claudio Baracchini, Christos Krogias, Andrei V. Alexandrov, Georgios Tsivgoulis
Primary Institution: National and Kapodistrian University of Athens
Hypothesis
What is the clinical relevance of detecting microembolic signals in patients with acute ischemic stroke?
Conclusion
Detecting microembolic signals helps clinicians understand the underlying mechanisms of stroke and tailor treatment for patients.
Supporting Evidence
- Microembolic signals are more common in patients with large artery atherosclerosis.
- Detection of microembolic signals can indicate conditions like covert cardioembolism.
- Microembolic signals are associated with a higher risk of stroke recurrence.
- Reduction in microembolic signals may serve as a surrogate marker for evaluating stroke prevention treatments.
Takeaway
Doctors can listen for tiny signals in the brain to figure out what caused a stroke and how to treat it better.
Methodology
This narrative review consolidates observational and randomized evidence on the prevalence and clinical relevance of microembolic signals in different acute ischemic stroke settings.
Limitations
Variability in timing and methods of microembolic signal detection may affect results.
Participant Demographics
Patients with acute ischemic stroke and transient ischemic attack, including various stroke subtypes.
Digital Object Identifier (DOI)
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