Molecular characterization of a long range haplotype affecting protein yield and mastitis susceptibility in Norwegian Red cattle
2011

Study of a Genetic Trait in Norwegian Red Cattle

Sample size: 2601 publication 10 minutes Evidence: high

Author Information

Author(s): Sodeland Marte, Grove Harald, Kent Matthew, Taylor Simon, Svendsen Morten, Hayes Ben J, Lien Sigbjørn

Primary Institution: Norwegian University of Life Sciences

Hypothesis

The long range haplotype from the Holstein-Friesian bull 1606 Frasse affects protein yield and mastitis susceptibility in Norwegian Red cattle.

Conclusion

The haplotype from the Holstein-Friesian bull 1606 Frasse is associated with increased milk protein content and increased susceptibility to mastitis in Norwegian Red cattle.

Supporting Evidence

  • The haplotype was associated with increased milk protein content.
  • The haplotype was also associated with increased susceptibility to mastitis.
  • The study used high throughput sequencing technology for molecular characterization.
  • A total of 269 new SNPs were revealed in the studied region.
  • The study involved 2601 sires from the Norwegian dairy herd recording system.

Takeaway

This study found that a specific genetic trait in Norwegian Red cattle can help produce more milk protein but also makes them more likely to get sick.

Methodology

Association mapping was performed using genotypes from 556 SNPs and daughter-yield-deviations from 2601 bulls.

Potential Biases

Potential bias due to selective breeding practices in the NRC population.

Limitations

The study may not account for all environmental factors affecting mastitis susceptibility.

Participant Demographics

The study involved Norwegian Red cattle, specifically focusing on sires and their daughters.

Statistical Information

P-Value

2.87E-5

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1471-2156-12-70

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