Gastroparesis in Patients with Inactive Crohn's Disease: A Case Series
Author Information
Author(s): Kristinsson Jón O, Hopman Wim PM, Oyen Wim JG, Drenth Joost PH
Primary Institution: Radboud University Medical Center
Hypothesis
What are the clinical characteristics of patients with inflammatory bowel disease and symptoms of upper gut dysmotility?
Conclusion
Patients with Crohn's disease can experience severe symptoms of gastroparesis even when there are no signs of active inflammation.
Supporting Evidence
- All patients had severely delayed gastric emptying with a mean t 1/2 of 234 minutes.
- None of the patients showed signs of active inflammation or obstruction.
- Symptoms persisted despite various treatments including tube feeding and surgery.
Takeaway
Some people with Crohn's disease can have stomach problems that make it hard for food to move through, even when their disease isn't active.
Methodology
The study involved reviewing medical records and assessing gastric emptying through scintigraphy, along with various endoscopic procedures.
Limitations
The study is limited by its small sample size and the lack of a control group.
Participant Demographics
All patients were females with a mean age of 38.6 years.
Digital Object Identifier (DOI)
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