Organic Papers
2011
(S,S)-Methyl 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
publication
Author Information
Author(s): Tricia Naicker, Thavendran Govender, Hendrik G. Kruger, Glenn E. M. Maguire
Primary Institution: University of KwaZulu Natal
Conclusion
The study presents a novel chiral organocatalyst with a tetrahydroisoquinoline backbone that exhibits a half-boat conformation.
Supporting Evidence
- The title compound is a novel chiral organocatalyst containing a tetrahydroisoquinoline framework.
- The absolute stereochemistry was confirmed to be S,S at the C1 and C9 positions by proton NMR spectroscopy.
- The N-containing six-membered ring assumes a half-boat conformation.
Takeaway
The researchers created a new type of molecule that can help speed up chemical reactions, and they figured out its shape.
Methodology
The compound was synthesized using a series of chemical reactions and characterized using NMR spectroscopy and X-ray crystallography.
Digital Object Identifier (DOI)
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