Cystic lymph node metastases of squamous cell carcinoma of Waldeyer's ring origin
1999

Cystic Lymph Node Metastases in Squamous Cell Carcinoma

Sample size: 123 publication Evidence: moderate

Author Information

Author(s): Regauer S, Mannweiler S, Anderhuber W, Gotschuli A, Berghold A, Schachenreiter J, Jakse R, Beham A

Primary Institution: University of Graz

Hypothesis

What is the frequency of cystic lymph node metastases in patients with squamous cell carcinoma of Waldeyer's ring?

Conclusion

Cystic lymph node metastases are common in patients with squamous cell carcinoma, particularly from the base of the tongue.

Supporting Evidence

  • 82% of patients had metastases in lymph nodes.
  • 39% of patients had only solid metastases.
  • 37% of patients had only cystic metastases.
  • Cystic metastases were more common in patients with SCC of the base of the tongue.

Takeaway

Doctors looked at 123 patients with throat cancer and found that many had cysts in their lymph nodes, especially those with cancer in the base of the tongue.

Methodology

Retrospective analysis of neck dissection specimens from patients with primary squamous cell carcinoma.

Participant Demographics

62 males and 14 females with tonsillar SCC, 38 males and 5 females with base of tongue SCC, and 2 males and 2 females with nasopharynx SCC.

Statistical Information

P-Value

P = 0.005

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690229

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