Immunonutrition in Operated-on Gastric Cancer Patients: An Update
2024

Immunonutrition in Operated-on Gastric Cancer Patients: An Update

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Triantafillidis John K., Malgarinos Konstantinos

Primary Institution: Metropolitan General Hospital, Athens, Greece

Hypothesis

The study aims to evaluate the effects of enteral immune nutrition (EIN) on immune responses and clinical outcomes in gastric cancer patients undergoing surgery.

Conclusion

Perioperative administration of enteral immune nutrition reduces postoperative complications and length of hospital stay but does not improve patient survival.

Supporting Evidence

  • Enteral immune nutrition enhances immune responses in gastric cancer patients.
  • Patients receiving EIN had shorter hospital stays and fewer postoperative complications.
  • Meta-analyses support the efficacy of EIN in reducing infectious complications.

Takeaway

Giving special nutrition to patients with stomach cancer before and after surgery helps them heal better and stay in the hospital for less time.

Methodology

The study conducted a systematic review and meta-analysis of clinical trials and studies on the effects of EIN in gastric cancer patients.

Potential Biases

Some studies had small sample sizes and heterogeneity in patient conditions, which could introduce bias.

Limitations

The studies included varied in patient nutritional status, product types, and administration periods, which may affect the results.

Participant Demographics

The study included gastric cancer patients, with some studies focusing on those with cachexia.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/biomedicines12122876

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